In UCSF's Center for Parasitic Diseases, lead compounds that are approved as safe and can be repurposed to treat neglected diseases are of particular interest. This includes screening of drug libraries to find safe lead compounds that may have previously unknown efficacy in treating diseases.
Currently, UCSF's Sakanari lab research includes searches for macrofilaricides for the organisms causing river blindness (Onchocerca volvulus) and lymphatic filariasis (Wuchereria bancrofti, Brugia malayi, and Brugia timori) using a model based of a Brugia pahangi model.
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